Hydrogen-Bonding Recognition-Induced Color Change of Gold Nanoparticles for Visual Detection of Melamine in Raw Milk and Infant Formula
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- 18 June 2009
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 131 (27), 9496-9497
- https://doi.org/10.1021/ja9037017
Abstract
The color change induced by triple hydrogen-bonding recognition between melamine and a cyanuric acid derivative grafted on the surface of gold nanoparticles can be used for reliable detection of melamine. Since such a color change can be readily seen by the naked eye, the method enables on-site and real-time detection of melamine in raw milk and infant formula even at a concentration as low as 2.5 ppb without the aid of any advanced instruments.Keywords
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