Clinical improvement and shrinkage of uterine fibroids after thermal ablation by magnetic resonance‐guided focused ultrasound surgery
- 26 September 2007
- journal article
- Published by Wiley in Ultrasound in Obstetrics & Gynecology
- Vol. 30 (5), 771-777
- https://doi.org/10.1002/uog.4099
Abstract
Objective Hysterectomy or myomectomy are the accepted treatments for symptomatic uterine fibroids. Heat ablation of uterine fibroids has been shown to be an effective alternative treatment. The aim of this study was to determine the clinical efficacy of non‐invasive thermal ablation by transcutaneous magnetic resonance‐guided high‐intensity focused ultrasound (MRgFUS) for the treatment of symptomatic uterine fibroids. Methods In this prospective study, MRgFUS ablation of uterine fibroids was performed in 35 symptomatic women scheduled for hysterectomy. Clinical symptoms, patient satisfaction and uterine size were determined at 1 month and 6 months after the procedure. Results This outpatient procedure was very well tolerated by all women. Sixty‐nine percent (24/35) of the treated patients reported either significant or partial improvement in symptoms. Treated fibroids decreased in volume by 12% and 15% at 1 and 6 months, respectively. Minor transient side‐effects were observed in two women. Six women underwent hysterectomy during the follow‐up period. Conclusion This study demonstrates the clinical efficacy of MRgFUS ablation of uterine fibroids. This novel, non‐invasive surgical approach may offer an alternative therapy for women with uterine fibroids. Copyright © 2007 ISUOG. Published by John Wiley & Sons, Ltd.Keywords
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