Osteoporosis in Healthy South Indian Males and the Influence of Life Style Factors and Vitamin D Status on Bone Mineral Density
Open Access
- 11 November 2014
- journal article
- Published by Hindawi Limited in Journal of Osteoporosis
- Vol. 2014, 1-5
- https://doi.org/10.1155/2014/723238
Abstract
Objective. To study the prevalence of osteoporosis and vitamin D deficiency in healthy men and to explore the influence of various life style factors on bone mineral density (BMD) and also to look at number of subjects warranting treatment.Methods. Ambulatory south Indian men aged above 50 were recruited by cluster random sampling. The physical activity, risk factors in the FRAX tool, BMD, vitamin D, and PTH were assessed. The number of people needing treatment was calculated, which included subjects with osteoporosis and osteopenia with 10-year probability of major osteoporotic fracture >20 percent and hip fracture >3 percent in FRAX India.Results. A total of 252 men with a mean age of 58 years were studied. The prevalence of osteoporosis and osteopenia at any one site was 20% (50/252) and 58%, respectively. Vitamin D deficiency (<20 ng/dL) was seen in 53%. On multiple logistic regression, BMI (OR 0.3;value = 0.04) and physical activity (OR 0.4;value < 0.001) had protective effect on BMD. Twenty-five percent warranted treatment.Conclusions. A significantly large proportion of south Indian men had osteoporosis and vitamin D deficiency. Further interventional studies are needed to look at reduction in end points like fractures in these subjects.
Keywords
This publication has 30 references indexed in Scilit:
- Osteoporosis in the European Union: medical management, epidemiology and economic burdenArchives of Osteoporosis, 2013
- Prevalence of osteoporosis in otherwise healthy Indian males aged 50 years and aboveArchives of Osteoporosis, 2013
- Changing Profile of Health and Function from Age 70 to 85 YearsGerontology, 2012
- Vitamin D status in India--its implications and remedial measures.2009
- Osteoporosis in MenThe New England Journal of Medicine, 2008
- FRAX™ and the assessment of fracture probability in men and women from the UKOsteoporosis International, 2008
- Gender equity & human development.2007
- Osteoporosis in MenEndocrinology and Metabolism Clinics of North America, 2007
- The development & characteristics of a physical activity questionnaire for epidemiological studies in urban middle class Indians.2000
- Mortality after all major types of osteoporotic fracture in men and women: an observational studyThe Lancet, 1999