The Evolving Treatment of Anal Cancer
Open Access
- 1 August 2001
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 136 (8), 886-891
- https://doi.org/10.1001/archsurg.136.8.886
Abstract
ANAL CANAL cancer is rare and only accounts for 1% to 6% of all anorectal neoplasms.1 It is important to distinguish anal canal from anal margin neoplasms, as the former are much more aggressive and therefore treated as such. The anatomic landmarks of the anal canal are the anorectal ring proximally and the anal verge distally.2 The anal margin is defined as the perianal skin extending 5 cm out from the anal verge. Most anal canal tumors (squamous, cloacogenic, basaloid, and transitional) behave in similar fashions and are collectively termed epidermoid carcinomas.This publication has 4 references indexed in Scilit:
- 17 Perianal and Anal Canal NeoplasmsPublished by Georg Thieme Verlag KG ,2019
- Concomitant radiotherapy and chemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European Organization for Research and Treatment of Cancer Radiotherapy and Gastrointestinal Cooperative Groups.Journal of Clinical Oncology, 1997
- Role of mitomycin in combination with fluorouracil and radiotherapy, and of salvage chemoradiation in the definitive nonsurgical treatment of epidermoid carcinoma of the anal canal: results of a phase III randomized intergroup study.Journal of Clinical Oncology, 1996
- Combined preoperative radiation and chemotherapy for squamous cell carcinoma of the anal canalCancer, 1983