Galactosylated cucurbituril-inclusion polyplex for hepatocyte-targeted gene delivery
Open Access
- 16 December 2009
- journal article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 46 (5), 692-694
- https://doi.org/10.1039/b920753h
Abstract
The work demonstrates a judicious approach to achieve hepatocyte cell-targeted highly efficient gene delivery by utilizing a supramolecular complex of galactosylated cucurbituril and dextran–spermine conjugates.Keywords
This publication has 20 references indexed in Scilit:
- Synergistic effects in gene delivery—a structure–activity approach to the optimisation of hybrid dendritic–lipidic transfection agentsChemical Communications, 2008
- Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trialThe Lancet, 2007
- Recent developments in the use of adenoviruses and immunotoxins in cancer gene therapyCancer Gene Therapy, 2007
- Targeted polymeric gene delivery for anti-angiogenic tumor therapyMacromolecular Research, 2007
- Soluble Flt-1 gene delivery using PEI-g-PEG-RGD conjugate for anti-angiogenesisJournal of Controlled Release, 2005
- Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 DiseaseScience, 2000
- Tailoring New Gene Delivery Designs for Specific TargetsJournal of Drug Targeting, 2000
- Cationic Liposomes for Gene TherapyAngewandte Chemie-International Edition, 1998
- A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.Proceedings of the National Academy of Sciences of the United States of America, 1995
- RetrovirusesScience, 1988