Diagnostic Performance of Dual-Energy CT for the Detection of Traumatic Bone Marrow Lesions in the Ankle: Comparison with MR Imaging
- 1 July 2012
- journal article
- research article
- Published by Radiological Society of North America (RSNA) in Radiology
- Vol. 264 (1), 164-173
- https://doi.org/10.1148/radiol.12112217
Abstract
Purpose:To evaluate prospectively the performance of noncalcium images reconstructed from dual-energy (DE) computed tomography (CT) for the diagnosis of bone marrow lesions in patients with acute ankle joint trauma in comparison with magnetic resonance (MR) images.Materials and Methods:The study had local ethics board approval, and written informed consent was obtained. Thirty consecutive patients (15 women; mean age, 34 years ± 11.8 [standard deviation]) underwent dual-source DE CT (80 kVp and 140 kVp with tin filter) and MR imaging within 1 day following acute ankle trauma. DE CT data were postprocessed by using a three-material decomposition algorithm for generating noncalcium images. MR and noncalcium images were graded by two blinded, independent readers using a four-point system (1 = distinct bone marrow lesion, 4 = no lesion); CT numbers in noncalcium images were calculated by a third reader. MR imaging interpretations served as the reference standard.Results:Interreader agreement for qualitative grading of DE CT images was substantial (κ = 0.66). The respective sensitivity, specificity, positive predictive value, and negative predictive value of DE CT for depicting distinct bone marrow lesions for both readers were 90.0% each, 80.5% and 81.6%, 25.4% and 26.5%, and 99.1% each. In regions without abnormality, CT numbers in noncalcium images gradually increased from proximal to distal location (P < .001). Significant differences in CT numbers were found in regions positive for bone marrow lesions compared with those that were negative (P < .001). CT numbers for the diagnosis of distinct bone marrow lesions according to MR imaging revealed areas under the receiver operating characteristic curve of 0.973, 0.813, and 0.758 for ankle mortise, talar dome, and talar body/head, respectively.Conclusion:Compared with MR images, distinct traumatic bone marrow lesions of the ankle joint can be diagnosed on noncalcium images reconstructed from DE CT with high sensitivity and excellent negative predictive value, but with moderate specificity and low positive predictive value.© RSNA, 2012This publication has 27 references indexed in Scilit:
- Traumatic bone bruising—A review articleEuropean Journal of Radiology, 2008
- Histopathological perspective on bone marrow oedema, reactive bone change and haemorrhageEuropean Journal of Radiology, 2008
- MRI of Acute Bone Bruises: Timing of the Appearance of Findings in a Swine ModelAmerican Journal of Roentgenology, 2008
- Bone marrow changes on STIR MR images of asymptomatic feet and anklesEuropean Radiology, 2007
- Bone Stress Injuries of the Ankle and FootThe American Journal of Sports Medicine, 2007
- Ankle and Foot Injuries: Analysis of MDCT FindingsAmerican Journal of Roentgenology, 2004
- Clinical Outcome of Edema-like Bone Marrow Abnormalities of the FootRadiology, 2002
- MR imaging of the foot and ankle: patterns of bone marrow signal abnormalitiesEuropean Radiology, 2001
- Occult cartilage and bone injuries of the knee: detection, classification, and assessment with MR imaging.Radiology, 1989
- Occult intraosseous fracture: detection with MR imaging.Radiology, 1988