Case Report: Rhabdomyolysis After Simvastatin Therapy in an HIV-Infected Patient with Chronic Renal Failure
- 1 December 2004
- journal article
- case report
- Published by Mary Ann Liebert Inc in AIDS Patient Care and STDs
- Vol. 18 (12), 687-690
- https://doi.org/10.1089/apc.2004.18.687
Abstract
We encountered a 49-year-old HIV-infected man with chronic renal insufficiency who developed rhabdomyolysis after treatment with simvastatin. He recovered after initiating hemodialysis and discontinuing oral medications. Rhabdomyolysis most likely resulted from an excessive blood concentration of simvastatin caused by concomitant use of fluconazole in the presence of renal insufficiency.Keywords
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