Effect of Different Levels of Maternally Derived Antibodies on Protection Against Infectious Bursal Disease Virus
- 1 January 2004
- journal article
- Published by American Association of Avian Pathologists (AAAP) in Avian Diseases
- Vol. 48 (1), 177-182
- https://doi.org/10.1637/5319
Abstract
Fertile eggs were obtained from three different broiler breeder flocks with different levels of virus neutralizing antibodies to infectious bursal disease virus. Egg yolk from these flocks was tested for antibody titers by the virus neutralization test. Flock I eggs had no antibodies, flock II had medium level antibodies (1:200-1600; geometric mean = 1:975), and flock III had a high level of antibodies (1:1600-6400; geometric mean = 1:3365). Chicks from the above flocks were challenged each with 10(2) 50% embryo infective dose of the IN serotype 1 variant virus at 1, 2, and 4 wk of age and examined at 5 and 11 days postchallenge. The average organ/body weight ratios were calculated and statistically analyzed. Chicks with no maternal antibodies were not protected at any age. Chicks with medium levels of maternal antibodies were protected when challenged at 1 and 2 wk of age. Chicks with high levels of maternally derived antibodies were protected when challenged at all the ages tested. The above results were statistically significant (P < 0.05).Keywords
This publication has 11 references indexed in Scilit:
- Subclinical Infectious Bursal Disease in an Integrated Broiler Production OperationJournal of Veterinary Diagnostic Investigation, 1992
- Susceptibility of chicken blood lymphoblasts and monocytes to infectious bursal disease virus (IBDV)Archiv für die gesamte Virusforschung, 1987
- Assessment by ELISA of passively acquired protection against infectious bursal disease virus in chickensAustralian Veterinary Journal, 1987
- Comparison of the efficacy of four inactivated infectious bursal disease oil emulsion vaccinesVeterinary Record, 1982
- Infectious Bursal Disease Emulsified Vaccine: Effect upon Neutralizing-Antibody Levels in the Dam and Subsequent Protection of the ProgenyAvian Diseases, 1979
- Immunization Studies with a Cell-Culture-Adapted Infectious Bursal Disease VirusAvian Diseases, 1979
- Susceptibility of chicks to infectious bursal disease (IBD) following vaccination of their parents with live IBD vaccineVeterinary Record, 1978
- Maternally derived antibody ? effect on susceptibility of chicks to infectious bursal diseaseAvian Pathology, 1976
- Immunosuppressive effect of infectious bursal agent on vaccination against Newcastle diseasePublished by Wiley ,1974
- An Apparently New Disease of Chickens: Avian NephrosisAvian Diseases, 1962