Referral Patterns, Demographic and Clinical Features, and Visual Prognosis of Turkish Patients with Sarcoid Uveitis
- 1 January 2007
- journal article
- Published by Informa UK Limited in Ocular Immunology and Inflammation
- Vol. 15 (4), 337-343
- https://doi.org/10.1080/09273940701375402
Abstract
The purpose of this study was to investigate the referral patterns, demographic and clinical features, and visual prognosis of patients with sarcoid uveitis seen at 2 tertiary eye care centers in Turkey. A retrospective study was made of 44 patients with uveitis associated with biopsy-confirmed or presumed sarcoidosis. Thirty-four patients (77%) were female and 10 (23%) were male. The mean age at onset of uveitis was 39.8 years. Twenty-seven patients (61%) were referred without a diagnosis of sarcoidosis and 17 (39%) patients were referred with a diagnosis of systemic sarcoidosis. The duration of uveitis prior to referral was 2-15 years in 52% of the patients in the former group. At presentation, 37 patients (84%) had bilateral and 7 patients (16%) had unilateral uveitis, and 17 patients (39%) had only anterior uveitis. The most common ocular findings were granulomatous keratic precipitates, persistent posterior synechiae, and snowball vitreous opacities. Kaplan-Meier survival analysis estimated the risk of recurrence as 30% at 6 months and 61% at 5 years. New complications developed in 18 patients. Potential visual acuity was better than 0.4 in 80% of eyes. The estimated risk of losing potential visual acuity by at least 2 lines was 7% at 6 months and 43% at 5 years. None of the eyes lost useful vision (> 0.1) under the authors' care. The referral patterns suggest underrecognition of sarcoidosis as a cause of uveitis in Turkey. The demographic and clinical features of these patients were mostly similar to those reported from other countries, suggesting that the diagnosis may not be difficult in Turkish patients but requires an increased awareness of the disease in this population.Keywords
This publication has 19 references indexed in Scilit:
- Racial and Ethnic Disparities in Sarcoidosis: From Genetics to SocioeconomicsClinics in Chest Medicine, 2006
- Standardization of Uveitis Nomenclature for Reporting Clinical Data. Results of the First International WorkshopAmerican Journal of Ophthalmology, 2005
- First presenting signs or symptoms of sarcoidosis in a Japanese populationJapanese Journal of Ophthalmology, 2005
- ORIGINAL ARTICLE Causes of Uveitis in a Referral Hospital in Ankara, TurkeyOcular Immunology and Inflammation, 2005
- Uveitis in Behçet disease: An analysis of 880 patientsAmerican Journal of Ophthalmology, 2004
- Demographic-related variations in posterior segment ocular sarcoidosisOphthalmology, 2004
- Prevalence of Behçet's disease in Istanbul, TurkeyInternational Journal of Dermatology, 2003
- Ocular involvement in sarcoidosisBritish Journal of Ophthalmology, 2000
- Uveitis as a presenting feature of chronic sarcoidosisEuropean Respiratory Journal, 1996
- Causes and frequency of blindness in patients with intraocular inflammatory disease.British Journal of Ophthalmology, 1996