New developments in MRI for target volume delineation in radiotherapy
- 1 September 2006
- journal article
- review article
- Published by Oxford University Press (OUP) in The British Journal of Radiology
- Vol. 79 (special__1), S2-S15
- https://doi.org/10.1259/bjr/41321492
Abstract
MRI is being increasingly used in oncology for staging, assessing tumour response and also for treatment planning in radiotherapy. Both conformal and intensity-modulated radiotherapy requires improved means of defining target volumes for treatment planning in order to achieve its intended benefits. MRI can add to the radiotherapy treatment planning (RTP) process by providing excellent and improved characterization of soft tissues compared with CT. Together with its multiplanar capability and increased imaging functionality, these advantages for target volume delineation outweigh its drawbacks of lacking electron density information and potential image distortion. Efficient MR distortion assessment and correction algorithms together with image co-registration and fusion programs can overcome these limitations and permit its use for RTP. MRI developments using new contrast media, such as ultrasmall superparamagnetic iron oxide particles for abnormal lymph node identification, techniques such as dynamic contrast enhanced MRI and diffusion MRI to better characterize tissue and tumour regions as well as ultrafast volumetric or cine MR sequences to define temporal patterns of target and organ at risk deformity and variations in spatial location have all increased the scope and utility of MRI for RTP. Information from these MR developments may permit treatment individualization, strategies of dose escalation and image-guided radiotherapy. These developments will be reviewed to assess their current and potential use for RTP and precision high dose radiotherapy.This publication has 84 references indexed in Scilit:
- Assessing the Impact of MRI on Determination of Planning Volumes for Conformal Prostate RadiotherapyInternational Journal of Radiation Oncology*Biology*Physics, 2005
- Pre-operative imaging of rectal cancer and its impact on surgical performance and treatment outcomeEuropean Journal of Surgical Oncology, 2005
- Pre‐operative assessment of extramural invasion and sphincteral involvement in rectal cancer by magnetic resonance imaging with phased‐array coilColorectal Disease, 2005
- Nasopharyngeal carcinomaThe impact of CT-scan and of MRI on staging, radiotherapy treatment planning, and outcome of the diseaseClinical Imaging, 2005
- Analyzing 3-tesla magnetic resonance imaging units for implementation in radiosurgeryJournal of Neurosurgery, 2005
- Clinical and anatomical guidelines in pelvic cancer contouring for radiotherapy treatment planningCancer/Radiothérapie, 2004
- Intensity-modulated radiotherapy with mri simulation to reduce doses received by erectile tissue during prostate cancer treatmentInternational Journal of Radiation Oncology*Biology*Physics, 2004
- Impact of magnetic resonance imaging versus CT on nasopharyngeal carcinoma: primary tumor target delineation for radiotherapyHead & Neck, 2004
- Advances in magnetic resonance imaging of brain tumoursCurrent Opinion in Neurology, 2003
- Prostate volumes defined by magnetic resonance imaging and computerized tomographic scans for three-dimensional conformal radiotherapyInternational Journal of Radiation Oncology*Biology*Physics, 1996