Hepatitis C: recent successes and continuing challenges in the development of improved treatment modalities
- 31 October 2009
- journal article
- review article
- Published by Elsevier BV in Current Opinion in Pharmacology
- Vol. 9 (5), 537-544
- https://doi.org/10.1016/j.coph.2009.08.008
Abstract
No abstract availableKeywords
This publication has 48 references indexed in Scilit:
- Toll-Like Receptor 3 Mediates Establishment of an Antiviral State against Hepatitis C Virus in Hepatoma CellsJournal of Virology, 2009
- Modulation of Hepatitis C Virus RNA Abundance by a Liver-Specific MicroRNAScience, 2005
- Production of infectious hepatitis C virus in tissue culture from a cloned viral genomeNature Medicine, 2005
- Hepatic Gene Expression Discriminates Responders and Nonresponders in Treatment of Chronic Hepatitis C Viral InfectionGastroenterology, 2005
- Crystal Structures of the RNA-dependent RNA Polymerase Genotype 2a of Hepatitis C Virus Reveal Two Conformations and Suggest Mechanisms of Inhibition by Non-nucleoside InhibitorsJournal of Biological Chemistry, 2005
- Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIFProceedings of the National Academy of Sciences, 2005
- Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site.Nature Structural & Molecular Biology, 1999
- Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell LineScience, 1999
- Interferon Alfa-2b Alone or in Combination with Ribavirin as Initial Treatment for Chronic Hepatitis CNew England Journal of Medicine, 1998
- Product Inhibition of the Hepatitis C Virus NS3 ProteaseBiochemistry, 1998