Evidence That Ser87 of BimEL Is Phosphorylated by Akt and Regulates BimEL Apoptotic Function
Open Access
- 1 January 2006
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 281 (2), 813-823
- https://doi.org/10.1074/jbc.m505546200
Abstract
No abstract availableKeywords
This publication has 53 references indexed in Scilit:
- Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activityThe Journal of cell biology, 2003
- Smad3 Potentiates Transforming Growth Factor β (TGFβ)-induced Apoptosis and Expression of the BH3-only Protein Bim in WEHI 231 B LymphocytesPublished by Elsevier BV ,2003
- Activation of ERK1/2 by ΔRaf-1 : ER* represses Bim expression independently of the JNK or PI3K pathwaysOncogene, 2003
- Nerve Growth Factor (NGF) Down-regulates the Bcl-2 Homology 3 (BH3) Domain-only Protein Bim and Suppresses Its Proapoptotic Activity by PhosphorylationPublished by Elsevier BV ,2002
- Bcl-XL Protects BimEL-induced Bax Conformational Change and Cytochrome c Release Independent of Interacting with Bax or BimELPublished by Elsevier BV ,2002
- Direct addition of BimL to mitochondria does not lead to cytochrome c releaseFEBS Letters, 2002
- Downregulation of Bim, a Proapoptotic Relative of Bcl-2, Is a Pivotal Step in Cytokine-Initiated Survival Signaling in Murine Hematopoietic ProgenitorsMolecular and Cellular Biology, 2001
- Suppression of transforming growth factor-β-induced apoptosis through a phosphatidylinositol 3-kinase/Akt-dependent pathwayOncogene, 1998
- Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase AktScience, 1997
- Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase‐1 and p70 S6 kinaseFEBS Letters, 1996