IL-6 plays a critical role in the synergistic induction of human serum amyloid A (SAA) gene when stimulated with proinflammatory cytokines as analyzed with an SAA isoform real-time quantitative RT-PCR assay system
- 5 January 2004
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 314 (2), 363-369
- https://doi.org/10.1016/j.bbrc.2003.12.096
Abstract
No abstract availableKeywords
This publication has 26 references indexed in Scilit:
- Long‐term safety and maintenance of clinical improvement following treatment with anakinra (recombinant human interleukin‐1 receptor antagonist) in patients with rheumatoid arthritis: Extension phase of a randomized, double‐blind, placebo‐controlled trialArthritis & Rheumatism, 2002
- Amyloid load and clinical outcome in AA amyloidosis in relation to circulating concentration of serum amyloid A proteinThe Lancet, 2001
- Regulation of β2-microglobulin expression in different human cell lines by proinflammatory cytokinesNephrology Dialysis Transplantation, 1999
- Direct Comparison of GAPDH, β-Actin, Cyclophilin, and 28S rRNA as Internal Standards for Quantifying RNA Levels under HypoxiaBiochemical and Biophysical Research Communications, 1999
- The combined inactivation of tumor necrosis factor and interleukin-6 prevents induction of the major acute phase proteins by endotoxinEuropean Journal of Immunology, 1998
- Mechanism for Biphasic Rel A· NF-κB1 Nuclear Translocation in Tumor Necrosis Factor α-stimulated HepatocytesPublished by Elsevier BV ,1997
- ROLE OF CYTOKINES IN RHEUMATOID ARTHRITISAnnual Review of Immunology, 1996
- A novel allelic variant of serum amyloic A, SAA1γ: genomic evidence, evolution, frequency, and implication as a risk factor for reactive systemic AA– amyloidosisHuman Molecular Genetics, 1995
- Characterization of amyloid A protein in human secondary amyloidosis: the predominant deposition of serum amyloid A1Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1995
- Impaired immune and acute-phase responses in interleukin-6-deficient miceNature, 1994