Characterization of TolC Efflux Pump Proteins from Pasteurella multocida

Abstract
Two TolC homologs, PM0527 and PM1980, were identified for Pasteurella multocida . A pm0527 mutant displayed increased susceptibility to a range of chemicals, including rifampin (512-fold) and acridine orange (128-fold). A pm1980 mutant showed increased susceptibility to rifampin, ceftazidime, and vancomycin.