Pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as novel antiproliferative agents: Exploration of core and headpiece structure–activity relationships
- 13 January 2007
- journal article
- research article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry Letters
- Vol. 17 (6), 1641-1645
- https://doi.org/10.1016/j.bmcl.2006.12.116
Abstract
No abstract availableKeywords
This publication has 11 references indexed in Scilit:
- Knockout drug screens.Nature Biotechnology, 2001
- Use of isogenic human cancer cells for high-throughput screening and drug discoveryNature Biotechnology, 2001
- p53 Signaling and Cell Cycle CheckpointsChemical Research in Toxicology, 2001
- The Hallmarks of CancerCell, 2000
- CDK inhibitors: positive and negative regulators of G1-phase progressionGenes & Development, 1999
- Cell-cycle arrest versus cell death in cancer therapyNature Medicine, 1997
- When Checkpoints FailCell, 1997
- p53, the Cellular Gatekeeper for Growth and DivisionCell, 1997
- p21--Negative Regulator of the Cell CycleExperimental Biology and Medicine, 1996
- Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21Nature, 1996