Psoriasis is associated with increased β-defensin genomic copy number
Top Cited Papers
- 2 December 2007
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature Genetics
- Vol. 40 (1), 23-25
- https://doi.org/10.1038/ng.2007.48
Abstract
Psoriasis is a common inflammatory skin disease with a strong genetic component. We analyzed the genomic copy number polymorphism of the β-defensin region on human chromosome 8 in 179 Dutch individuals with psoriasis and 272 controls and in 319 German individuals with psoriasis and 305 controls. Comparisons in both cohorts showed a significant association between higher genomic copy number for β-defensin genes and risk of psoriasis.This publication has 15 references indexed in Scilit:
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