Detection of TNT and its metabolites in body fluids of laboratory animals and in occupational exposed humans
- 1 January 1986
- journal article
- research article
- Published by Informa UK Limited in Journal of Energetic Materials
- Vol. 4 (1-4), 305-313
- https://doi.org/10.1080/07370658608011346
Abstract
Metabolites of 2,4,6-trinitrotoluene (TNT) were found in the urine of rats and in the blood of rabbits fed with TNT, in the urine of rats exposed to TNT by skin absorption, and in the urine of TNT munition workers. Urine and blood extracts were analyzed by liquid-chromatography/mass spectrometry (LC/MS), The metabolites found included untransformed TNT, 2-amino-4,6-dinitrotoluene (2-A), 4-amino-2,6-dinitrotoluene (4-A), 2,4-diamino-6-nitro-toluene (2-4-DA) and 2,6-diamino-4-nitrotoluene (2,6-DA).Keywords
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