Synthesis of core–shell coordination polymer nanoparticles (CPNs) for pH-responsive controlled drug release
- 24 April 2012
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 48 (48), 5995-5997
- https://doi.org/10.1039/c2cc30877k
Abstract
Four types of physiologically unstable anticancer “drug-metal” CPNs were “shelled” with pH-responsive “ligand-metal” CPs, which gives rise to a significant release of drug molecules under designated pH conditions and exhibited a higher cytotoxicity against HeLa cells than core CPNs and free drug.Keywords
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