Prevention of the First Occurrence of Neural-Tube Defects by Periconceptional Vitamin Supplementation
- 24 December 1992
- journal article
- clinical trial
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 327 (26), 1832-1835
- https://doi.org/10.1056/nejm199212243272602
Abstract
The risk of recurrent neural-tube defects is decreased in women who take folic acid or multivitamins containing folic acid during the periconceptional period. The extent to which such supplementation can reduce the first occurrence of defects is not known.Keywords
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