Functional Decline in Peripheral Arterial Disease

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Abstract
Cross-sectional studies demonstrate that distinct types of leg symptoms reported by patients with peripheral arterial disease (PAD) in the lower extremities are associated with varying degrees of functional impairment.1,2 Severity of PAD, as measured by the ankle brachial index (ABI), is also associated with the degree of functional impairment.2,3 However, relationships between the ABI, leg symptoms, and functional decline are unknown.