Pharmacokinetics of Imipenem/Cilastatin Burn Intensive Care Unit Patients Undergoing High-Dose Continuous Venovenous Hemofiltration
- 4 December 2016
- journal article
- research article
- Published by Wiley in Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy
- Vol. 36 (12), 1229-1237
- https://doi.org/10.1002/phar.1866
Abstract
Efficient removal of I/C by high-dose CVVH, a high overall clearance, and a high volume of distribution in burn intensive care unit patients undergoing this CRRT method warrant aggressive dosing to treat serious infections effectively depending on the infection site and/or pathogen.Keywords
Funding Information
- Dean's Enhancement Program for Seed Research Grants
- University of Tennessee College of Pharmacy
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