Expressing the human genome
- 15 February 2001
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 409 (6822), 832-833
- https://doi.org/10.1038/35057011
Abstract
We have searched the human genome for genes encoding new proteins that may be involved in three nuclear gene expression processes: transcription, pre-messenger RNA splicing and polyadenylation. A plethora of potential new factors are implicated by sequence in nuclear gene expression, revealing a substantial but selective increase in complexity compared with Drosophila melanogaster and Caenorhabditis elegans. Although the raw genomic information has limitations, its availability offers new experimental approaches for studying gene expression.Keywords
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