MALAT1 is a prognostic factor in glioblastoma multiforme and induces chemoresistance to temozolomide through suppressing miR-203 and promoting thymidylate synthase expression
Open Access
- 8 February 2017
- journal article
- Published by Impact Journals, LLC in Oncotarget
- Vol. 8 (14), 22783-22799
- https://doi.org/10.18632/oncotarget.15199
Abstract
// <![CDATA[ $('.header-date').hide();$('#titleAuthors').hide();$('#abstractHeader').hide(); // ]]> Wei Chen1, 2, 3, *, Xin-Ke Xu1, *, Jun-Liang Li1, 2, *, Kuan-Kei Kong1, 2, Hui Li4, Cheng Chen1, Jing He1, Fangyu Wang1, Ping Li1, Xiao-Song Ge5, Fang-Cheng Li1, 2 1Department of Neurosurgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, China 2Department of Neurosurgery, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou 510120, China 3State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, 430071, China 4Department of Respiratory, The First People's Hospital of Foshan, Sun Yat-Sen University, Guangdong Foshan 528000, China 5Department of Oncology, The Affiliated Hospital of Jiangnan University, Wuxi 214062, Jiangsu, China *These authors contributed equally to this work Correspondence to: Fang-Cheng Li, email: sjwklfc@126.com Xiao-Song Ge, email: Stanly8345@163.com Keywords: MALAT1, temozolomide, chemoresistance, miR-203, thymidylate synthase Received: December 06, 2016 Accepted: January 22, 2017 Published: February 08, 2017Keywords
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