Possible donor–recipient bartonellosis transmission in a pediatric liver transplant
- 12 November 2008
- journal article
- case report
- Published by Wiley in Transplant Infectious Disease
- Vol. 10 (6), 431-433
- https://doi.org/10.1111/j.1399-3062.2008.00326.x
Abstract
Bartonella henselae is the causative agent of cat-scratch disease and other disorders, including hepatosplenic granulomatosis. This infection has only rarely been reported after solid organ transplantation, where it can mimic the more common post-transplant lymphoproliferative disease. Here we present a case of asymptomatic B. henselae hepatic and lymph nodal granulomatosis in a pediatric patient who had received orthotopic liver transplant 2 months before; we hypothesize that the causative agent was transmitted from the donor. This infection developed early in the post-transplant period; the disease involved only the graft liver and the regional lymph nodes, and the patient did not have a cat or any history of contact, scratches, or bites by a cat. In our patient this infection resolved successfully with a combination of 2 associated antibiotics and reduction of immunosuppressive therapy.Keywords
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