ABO blood group distribution and major cardiovascular risk factors in patients with acute myocardial infarction
- 1 April 2008
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Blood Coagulation & Fibrinolysis
- Vol. 19 (3), 231-234
- https://doi.org/10.1097/mbc.0b013e3282f54522
Abstract
We aimed to investigate whether there is an association between ABO blood groups, cardiovascular risk factors and myocardial infarction (MI) in a Turkish cohort. Four hundred and seventy-six patients with acute ST elevation MI (mean age 56.7+/-11.7; 80% men) and 203 age and sex matched healthy subjects were enrolled in the study. ABO blood group distribution of patients was compared with control group. Furthermore, in each ABO blood group, frequency of major cardiac risk factors was determined to find any correlation between blood groups and cardiovascular risk factors. The distribution of ABO blood groups in patients versus control group was A in 43.1 versus 44.3%, B in 15.1 versus 15.3%, AB in 10.7 versus 12.3% and O in 31.1 versus 28.1% (P>0.05 for all). ABO blood group distribution of both patients and control group was concordant with the official data from general Turkish population. The frequency of cardiovascular risk factors was similar in patients with different blood groups; however, the patients with blood group A were younger (P=0.004) and coronary artery disease detection age was lower (P=0.001) than those with the other blood groups. The distribution of ABO blood groups in patients with MI was quite similar to that in control group and that of general Turkish population, which supports the idea that ABO blood group might not be significantly associated with the development of MI. Association of ABO blood group distribution with cardiovascular risk factors, coronary artery disease and MI needs to be clarified with multicenter, prospective and large-scale studies.Keywords
This publication has 16 references indexed in Scilit:
- Correlation between ABO blood groups, major risk factors, and coronary artery diseaseInternational Journal of Cardiology, 2006
- Functional Effects of the ABO Locus Polymorphism on Plasma Levels of von Willebrand Factor, Factor VIII, and Activated Partial Thromboplastin TimeArteriosclerosis, Thrombosis, and Vascular Biology, 2000
- von Willebrand Factor, C-Reactive Protein, and 5-Year Mortality in Diabetic and Nondiabetic SubjectsArteriosclerosis, Thrombosis, and Vascular Biology, 1999
- Hemostatic Factors and the Risk of Myocardial Infarction or Sudden Death in Patients with Angina PectorisThe New England Journal of Medicine, 1995
- Factor VIII, ABO blood group and the incidence of ischaemic heart diseaseBritish Journal of Haematology, 1994
- ABO blood group and ischaemic heart disease in British men.BMJ, 1990
- ABO blood group system, age, sex, risk factors and cardiac infarctionArchives of Gerontology and Geriatrics, 1985
- Prevalence of Total Coronary Occlusion during the Early Hours of Transmural Myocardial InfarctionThe New England Journal of Medicine, 1980
- AN ASSOCIATION BETWEEN ABO BLOOD-GROUP DISTRIBUTION AND GEOGRAPHICAL DIFFERENCES IN DEATH-RATESThe Lancet, 1977
- ABO blood group and cardiovacular disease the Framingham studyAtherosclerosis, 1976