Cytochrome c6A is a funnel for thiol oxidation in the thylakoid lumen
- 29 March 2006
- journal article
- Published by Wiley in FEBS Letters
- Vol. 580 (9), 2166-2169
- https://doi.org/10.1016/j.febslet.2006.03.052
Abstract
Cytochrome c6A is a dithio-cytochrome recently discovered in land plants and green algae, and believed to be derived from the well-known cytochrome c6. The function of cytochrome c6A is unclear. We propose that it catalyses the formation of disulphide bridges in thylakoid lumen proteins in a single-step disulphide exchange reaction, with subsequent transfer of the reducing equivalents to plastocyanin. The haem group of cytochrome c6A acts as an electron sink, allowing rapid resolution of a radical intermediate formed during reoxidation of cytochrome c6A. Our model is consistent with previously published data on mutant plants, and the likely evolution of the proteinKeywords
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