Prevalence of Metabolic Syndrome in Pakistan
- 1 September 2008
- journal article
- review article
- Published by Mary Ann Liebert Inc in Metabolic Syndrome and Related Disorders
- Vol. 6 (3), 171-175
- https://doi.org/10.1089/met.2008.0005
Abstract
Over the past two decades, there has been a striking increase in the number of people with metabolic syndrome. The prevalence of metabolic syndrome varies due to lack of an internationally agreed upon definition. Considering the increased cardiovascular risk among Asian people, a lower cutoff for waist circumference is defined. Obesity in terms of waist circumference is found to be 46–68% of the Pakistani population, with a strong association found between arm fat and insulin insensitivity. In studying dyslipidemia, hypertriglyceridemia is found in 27–54% of the population, whereas 68–81% have low levels of high-density lipoprotein (HDL). Fifty percent were found to be at high risk of metabolic syndrome and as being hypertensive. With the high prevalence of all of these metabolic risk factors, the prevalence of metabolic syndrome in Pakistan according to different definitions is reported to be from 18% to 46%, comparable to the data from other South Asian countries. Thus, metabolic syndrome should be considered as a prime target for preventive medicine. The primary management goals for metabolic syndrome are to reduce the risks of cardiovascular disease and diabetes. Lifestyle-related risk factors are associated with the metabolic syndrome and diabetes. Unless preventive programs are properly designed and implemented, we will continue to treat the majority of the cases after they have already developed the complications. A prospective primary prevention study is underway in Pakistan that will help to create a base for public awareness strategies and nationwide surveillance and prevention programs against noncommunicable diseases.Keywords
This publication has 17 references indexed in Scilit:
- Prevalence of overweight and obesity and their association with hypertension and diabetes mellitus in an Indo-Asian populationCMAJ : Canadian Medical Association Journal, 2006
- High prevalence of obesity and associated risk factors in urban children in India and Pakistan highlights immediate need to initiate primary prevention program for diabetes and coronary heart disease in schoolsDiabetes Research and Clinical Practice, 2006
- Waist circumference criteria for the diagnosis of abdominal obesity are not applicable uniformly to all populations and ethnic groupsNutrition, 2005
- The clinical picture of metabolic syndromePostgraduate Medicine, 2004
- Insulin resistance syndrome (metabolic syndrome) and obesity in Asian Indians: evidence and implicationsNutrition, 2004
- Children`s Health is Insulin and Lipid DependentPakistan Journal of Nutrition, 2004
- Diabetes Risk Factors in Middle Income Pakistani School ChildrenPakistan Journal of Nutrition, 2003
- Low-Density Lipoprotein Size and Cardiovascular Disease: A ReappraisalJournal of Clinical Endocrinology & Metabolism, 2003
- Genetics of the metabolic syndromeBritish Journal of Nutrition, 2000
- Pakistan National Diabetes Survey: Prevalence of Glucose Intolerance and Associated Factors in Shikarpur, Sindh ProvinceDiabetic Medicine, 1995