Suprasellar germinoma
- 1 July 1978
- journal article
- Published by Journal of Neurosurgery Publishing Group (JNSPG) in Journal of Neurosurgery
- Vol. 49 (1), 41-48
- https://doi.org/10.3171/jns.1978.49.1.0041
Abstract
The clinical features of 18 cases of suprasellar germinoma were reviewed, and the following points stressed: 1) The incidence of intracranial germinoma and teratoma seems to be much higher in Japan than elsewhere. 2) Germinomas in the pineal region, the third ventricle, and the lateral ventricle were observed to be predominant in males. In suprasellar germinoma, however, males were not affected predominantly and the male:female ratio was 1:1. 3) Suprasellar germinomas caused three symptoms: diabetes insipidus, visual disturbances, and pituitary dysfunctions. 4) Pituitary functions were disturbed to various degrees. Some cases showed hypopituitarism but some showed an elevation of plasma concentrations of cortisol or luteinizing hormone and follicle stimulating hormone. 5) Some abnormalities showing a suprasellar mass were usually found on neuroradiological examination. 6) Suprasellar germinomas were very sensitive to radiotherapy and some of them rapidly disappeared on follow-up computerized tomography scanning after irradiation with as little as 1200 rads.Keywords
This publication has 11 references indexed in Scilit:
- Evaluation of Sellar and Parasellar Masses by Computed TomographyRadiology, 1976
- A female case of the HCG-producing ectopic pinealoma associated with precocious puberty.Endocrinologia Japonica, 1976
- Intracranial human chorionic gonadotropin-secreting tumor with precocious pubertyThe Journal of Pediatrics, 1975
- PRIMARY SUPRASELLAR ATYPICAL TERATOMABrain, 1974
- Ectopic pinealoma in the region of the optic chiasmJournal of Neurosurgery, 1971
- Statistical Reevaluation of Pinealoma and Related Tumors in JapanJournal of Neurosurgery, 1969
- The plasma sugar, free fatty acid, cortisol, and growth hormone response to insulin, and the comparison of this procedure with other tests of pituitary and adrenal function. II. In patients with hypothalamic or pituitary dysfunction or anorexia nervosa.JCI Insight, 1966
- Effect of Altered Thyroid Function Upon Steroid Circadian Rhythms in Man1Journal of Clinical Endocrinology & Metabolism, 1963
- Precocious puberty due to secreting chorionepithelioma (teratoma) of the brainThe Journal of Pediatrics, 1961
- SIGNIFICANCE OF THE CONCENTRATION OF NONPROTEIN-BOUND PLASMA CORTISOL IN NORMAL SUBJECTS, CUSHING'S SYNDROME, PREGNANCY, AND DURING ESTROGEN THERAPY*†Journal of Clinical Endocrinology & Metabolism, 1960