Gene Expression Signatures Predict Outcome in Non–Muscle-Invasive Bladder Carcinoma: A Multicenter Validation Study
Open Access
- 15 June 2007
- journal article
- research article
- Published by American Association for Cancer Research (AACR) in Clinical Cancer Research
- Vol. 13 (12), 3545-3551
- https://doi.org/10.1158/1078-0432.ccr-06-2940
Abstract
Purpose: Clinically useful molecular markers predicting the clinical course of patients diagnosed with non–muscle-invasive bladder cancer are needed to improve treatment outcome. Here, we validated four previously reported gene expression signatures for molecular diagnosis of disease stage and carcinoma in situ (CIS) and for predicting disease recurrence and progression.Keywords
Other Versions
This publication has 17 references indexed in Scilit:
- Concordance among Gene-Expression–Based Predictors for Breast CancerNew England Journal of Medicine, 2006
- Prediction of recurrence in Ta urothelial cell carcinoma by real-time quantitative PCR analysis: A microarray validation studyInternational Journal of Cancer, 2006
- Gene Expression Profiling of Progressive Papillary Noninvasive Carcinomas of the Urinary BladderClinical Cancer Research, 2005
- A Molecular Signature in Superficial Bladder Carcinoma Predicts Clinical OutcomeClinical Cancer Research, 2005
- Bladder Cancer Outcome and Subtype Classification by Gene ExpressionClinical Cancer Research, 2005
- A Gene-Expression Signature as a Predictor of Survival in Breast CancerNew England Journal of Medicine, 2002
- A molecular signature of metastasis in primary solid tumorsNature Genetics, 2002
- Gene-expression profiles predict survival of patients with lung adenocarcinomaNature Medicine, 2002
- Gene expression profiling predicts clinical outcome of breast cancerNature, 2002
- Isolation of biologically active ribonucleic acid from sources enriched in ribonucleaseBiochemistry, 1979