Vitamin E Can Protect against Ultraviolet Radiation-Induced Cataract in Albino Rats
- 1 October 2004
- journal article
- Published by S. Karger AG in Ophthalmic Research
- Vol. 36 (5), 264-269
- https://doi.org/10.1159/000081206
Abstract
To investigate if vitamin E protects against ultraviolet B radiation (UVB)-induced cataract. Albino Sprague-Dawley rats were divided into two groups: one group was fed vitamin E, while the other group was used as a control. Both groups were exposed to UVB. The rats were sacrificed, lenses extracted, forward light scattering was measured, and vitamin E and glutathione (GSH) contents were determined. Lenses in the vitamin E group developed slight opacities, while lenses in the control group developed nuclear cataracts. Forward light scattering in lenses of the control group was higher than in lenses in the vitamin-E-supplemented group. Vitamin E and GSH concentrations were higher in lenses treated with vitamin E than in the untreated group. Vitamin E protects the lens against UVB-induced cataract. Vitamin E protects directly as an antioxidant and/or indirectly through increased levels of GSH.Keywords
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