Clinical Outcomes of 5358 Patients Undergoing Direct Open Bypass or Endovascular Treatment for Aortoiliac Occlusive Disease: A Systematic Review and Meta-Analysis
- 1 August 2013
- journal article
- research article
- Published by International Society of Endovascular Specialists in Journal of Endovascular Therapy
- Vol. 20 (4), 443-455
- https://doi.org/10.1583/13-4242.1
Abstract
Purpose To examine clinical outcomes of endovascular and open bypass treatment for aortoiliac occlusive disease (AIOD). Methods Multiple databases were systematically searched to identify studies on open and endovascular treatment for AIOD published from 1989 to 2010. Studies were independently reviewed for eligibility criteria. Study selection and assessment of methodological quality were performed by two independent reviewers. Assuming between-study heterogeneity due to biases inherent to observational studies, a random effects model (DerSimonian-Laird method) was used for calculation of weighted proportions. Pooled weighted proportions or weighted means are reported. Twenty-nine open bypass studies (3733 patients) and 28 endovascular treatment studies (1625 patients) were analyzed. Results Weighted mean patient age was 60.4 years for open bypass and 60.8 years for endovascular treatment. Poor preoperative runoff was greater in the open bypass group (50.0% vs. 24.6%, pConclusion Although this study was limited by a paucity of randomized control trials, these results demonstrate superior durability for open bypass, although with longer LOS and increased risk for complications and mortality, when compared to the endovascular approach.Keywords
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