A peptide-catalyzed asymmetric Stetter reaction
- 29 November 2004
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- Vol. 36 (2), 195-197
- https://doi.org/10.1039/b414574g
Abstract
Thiazolylalanine, in appropriately functionalized form, has been found to function as an enantioselective catalyst for an intramolecular Stetter reaction. Incorporation of the residue in a number of environments has resulted in a family of catalysts that promote the cyclization of a test substrate with up to 81% enantiomeric excess.Keywords
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