Highly Enantioselective Transfer Hydrogenation of Quinolines Catalyzed by Gold Phosphates: Achiral Ligand Tuning and Chiral‐Anion Control of Stereoselectivity

Abstract

A little gold goes a long way: as little as 0.01 mol % of chiral gold phosphate is sufficient to afford the asymmetric transfer hydrogenation of quinolines with high stereoselectivity (up to 98 % ee). The achiral ligands on gold were found to have considerable effect on the catalytic efficiency.