Effect of a Primary Care Management Intervention on Mental Health–Related Quality of Life Among Survivors of Sepsis

Abstract

Sepsis is a major health problem worldwide.¹ It has been estimated that sepsis occurred in 2% of hospitalized patients in the United States in 2008, and incidence is expected to increase further in the future, with an even higher incidence in developing countries.² The risk of dying from sepsis has decreased in recent decades, owing to earlier detection and more effective treatment.³ Although more patients survive sepsis and are increasingly discharged from the hospital,⁴ they often experience functional disability, cognitive impairment, and psychiatric morbidity,^5,6 resulting in diminished health-related quality of life,⁷ increased health care costs,^8,9 and burden on patients and their families.^7,10