Ocular metastases
- 7 December 2012
- journal article
- Published by Springer Science and Business Media LLC in Eye
- Vol. 27 (2), 137-141
- https://doi.org/10.1038/eye.2012.252
Abstract
The eye is a rare site for disseminated malignancy because of the absence of a lymphatic system. Metastases to the ocular structures occur by haematogenous spread and therefore the parts of the eye with the best vascular supply are most likely to be affected. Many patients with Stage 4 carcinomatosis (distal metastatic spread) already have a history of a previous primary cancer. However, this is not always the case for lung cancer as this can metastasise early to the uveal tract and therefore the ophthalmologist may be the first to discover the presence of terminal metastatic disease. Broadly speaking, treatment options are focused on improving the patients' quality of life if visual acuity is threatened. Long-term side effects of treatment need to be considered as systemic cancer treatments and therefore patient life expectancy is improving. In this manuscript, presented at the Cambridge symposium 2012, the diagnosis and challenges involved in the management of ocular metastases are presented.Keywords
This publication has 21 references indexed in Scilit:
- Choroidal Metastasis as a Presenting Manifestation of Lung CancerMedicine, 2012
- Photodynamic therapy for choroidal metastasis from carcinoid tumorAmerican Journal of Ophthalmology, 2004
- Uveal metastasis from breast cancer in 264 patientsAmerican Journal of Ophthalmology, 2003
- Transvitreal fine needle aspiration biopsy: The influence of intraocular lesion size on diagnostic biopsy resultEye, 2001
- Plaque radiotherapy for the management of uveal metastasisCurrent Opinion in Opthalmology, 1998
- Survey of 520 Eyes with Uveal MetastasesOphthalmology, 1997
- Plaque Radiotherapy for the Management of Uveal MetastasisAmerican Journal of Ophthalmology, 1997
- Frequency of ocular metastases in patients dying of cancer in eye bank populations.British Journal of Ophthalmology, 1996
- Carcinoma Metastatic to the Eye and OrbitAmerican Journal of Ophthalmology, 1974
- The Incidence of Ocular Metastatic CarcinomaAmerican Journal of Ophthalmology, 1971