Racial disparities in surgical treatment and survival of epithelial ovarian cancer in United States
- 2 November 2007
- journal article
- research article
- Published by Wiley in Journal of Surgical Oncology
- Vol. 97 (2), 103-107
- https://doi.org/10.1002/jso.20932
Abstract
Objective To compare the racial differences in treatment and survival of epithelial ovarian cancer patients. Methods Data were obtained from the Surveillance, Epidemiology, and End Results Program between 1988 and 2001 and analyzed using Kaplan–Meier methods and Cox proportional hazards regression. Results Of the 24,038 women, 22,407 (93.2%) were non‐Hispanic White, and 1,631 (6.8%) were African‐American. Median age of Whites versus African‐Americans was 65 versus 63 years, respectively (P < 0.001). Of the patients with early‐stage (I–II) disease, 38.8% of Whites underwent lymphadenectomy with their primary surgery compared to only 32.8% of African‐Americans (P = 0.005). In the overall study group, the 5‐year disease‐specific survival of Whites was significantly higher compared to the African‐Americans (44.1% vs. 40.7%, P = 0.001). On multivariable analysis, age, race, stage, cell type, and grade of disease were all independent prognostic factors for survival. Conclusion Our data suggest that race is an independent prognostic factor for survival in epithelial ovarian cancer. In addition, African‐Americans with early‐stage cancer were less likely to undergo lymphadenectomy with their staging procedure. Furthermore, patient/physician education is needed to increase the number of patients undergoing surgical staging procedures for epithelial ovarian cancer. J. Surg. Oncol. 2008;97:103–107.Keywords
This publication has 20 references indexed in Scilit:
- Racial Disparities in Late Survival after Rectal Cancer SurgeryJournal of the American College of Surgeons, 2006
- Role of lymphadenectomy in the management of grossly apparent advanced stage epithelial ovarian cancerAmerican Journal of Obstetrics and Gynecology, 2006
- Ovarian cancer in younger vs older women: a population-based analysisBritish Journal of Cancer, 2006
- Racial disparity in survival among patients with advanced/recurrent endometrial adenocarcinomaCancer, 2006
- Race/ethnic variations in ovarian cancer mortality in the United States, 1992-1997Cancer, 2003
- Studying Radiation Therapy Using SEER-Medicare-Linked DataMedical Care, 2002
- Survival among U.S. Women with Invasive Epithelial Ovarian CancerGynecologic Oncology, 2002
- Racial differences in endometrial cancer survival: The black/white cancer survival studyObstetrics & Gynecology, 1996
- Sonographic visualization of the ovaries throughout pregnancyObstetrics & Gynecology, 1996
- Cancer statistics for African Americans, 1996CA: A Cancer Journal for Clinicians, 1996