A targeted mouse Brca1 mutation removing the last BRCT repeat results in apoptosis and embryonic lethality at the headfold stage
- 3 May 2001
- journal article
- Published by Springer Science and Business Media LLC in Oncogene
- Vol. 20 (20), 2544-2550
- https://doi.org/10.1038/sj.onc.1204363
Abstract
Oncogene is one of the world’s leading cancer journals. It is published weekly and covers all aspects of the structure and function of Oncogenes. Oncogene also publishes 8 Reviews issues a year, on a broad range of topics.Keywords
This publication has 41 references indexed in Scilit:
- Association of BRCA1 with the hRad50-hMre11-p95 Complex and the DNA Damage ResponseScience, 1999
- Centrosome Amplification and a Defective G2–M Cell Cycle Checkpoint Induce Genetic Instability in BRCA1 Exon 11 Isoform–Deficient CellsMolecular Cell, 1999
- Partial rescue of Brca15–6 early embryonic lethality by p53 or p21 null mutationNature Genetics, 1997
- BRCA1 mutations and phenotypeZeitschrift für Krebsforschung und Klinische Onkologie, 1997
- Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.Genes & Development, 1996
- The Tumor Suppressor Gene Brca1 Is Required for Embryonic Cellular Proliferation in the MouseCell, 1996
- Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype–phenotype correlationNature Genetics, 1995
- Isolation of the Mouse Homologue of BRCA1 and Genetic Mapping to Mouse Chromosome 11Genomics, 1995
- Tumor spectrum analysis in p53-mutant miceCurrent Biology, 1994
- Expression pattern of the mouse T gene and its role in mesoderm formationNature, 1990