High-resolution imaging reveals highly selective nonface clusters in the fusiform face area
- 6 August 2006
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature Neuroscience
- Vol. 9 (9), 1177-1185
- https://doi.org/10.1038/nn1745
Abstract
A region in ventral human cortex (fusiform face area, FFA) thought to be important for face perception responds strongly to faces and less strongly to nonface objects. This pattern of response may reflect a uniform face-selective neural population or activity averaged across populations with heterogeneous selectivity. Using high-resolution functional magnetic resonance imaging (MRI), we found that the FFA has a reliable heterogeneous structure: localized subregions within the FFA highly selective to faces are spatially interdigitated with localized subregions highly selective to different object categories. We found a preponderance of face-selective responses in the FFA, but no difference in selectivity to faces compared to nonfaces. Thus, standard fMRI of the FFA reflects averaging of heterogeneous highly selective neural populations of differing sizes, rather than higher selectivity to faces. These results suggest that visual processing in this region is not exclusive to faces. Overall, our approach provides a framework for understanding the fine-scale structure of neural representations in the human brain.Keywords
This publication has 38 references indexed in Scilit:
- A Cortical Region Consisting Entirely of Face-Selective CellsScience, 2006
- Object-Selective Cortex Exhibits Performance-Independent Repetition SuppressionJournal of Neurophysiology, 2006
- Mapping Cortical Activity Elicited with Electrical Microstimulation Using fMRI in the MacaqueNeuron, 2005
- Separate Face and Body Selectivity on the Fusiform GyrusJournal of Neuroscience, 2005
- Selectivity for the Human Body in the Fusiform GyrusJournal of Neurophysiology, 2005
- fMRI-Adaptation Reveals Dissociable Neural Representations of Identity and Expression in Face PerceptionJournal of Neurophysiology, 2004
- Faces and objects in macaque cerebral cortexNature Neuroscience, 2003
- Distributed and Overlapping Representations of Faces and Objects in Ventral Temporal CortexScience, 2001
- Vase or Face? A Neural Correlate of Shape-Selective Grouping Processes in the Human BrainJournal of Cognitive Neuroscience, 2001
- Optical Imaging of Functional Organization in the Monkey Inferotemporal CortexScience, 1996