Kinanthraquinone, a new anthraquinone carboxamide isolated from Streptomyces reveromyceticus SN-593-44
- 6 February 2018
- journal article
- research article
- Published by Springer Science and Business Media LLC in The Journal of Antibiotics
- Vol. 71 (4), 480-482
- https://doi.org/10.1038/s41429-017-0020-0
Abstract
A new anthraquinone derivative, kinanthraquinone (1) was isolated from Streptomyces reveromyceticus SN-593-44. Its structure was determined by the combination of spectroscopic methods including NMR and MS. Kinanthraquinone had a characteristic carboxamide group and was a rare class of metabolite as an anthraquinone derivative isolated from microbes. It showed moderate cytotoxocity against HL-60 and srcts-NRK cell with IC50 value of 7.9 and 10 μM, respectively.Keywords
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