Perceived Stress in Obsessive–Compulsive Disorder is Related with Obsessive but Not Compulsive Symptoms
Open Access
- 1 January 2013
- journal article
- research article
- Published by Frontiers Media SA in American Journal of Translational Research
- Vol. 4, 21
- https://doi.org/10.3389/fpsyt.2013.00021
Abstract
Obsessive-compulsive disorder (OCD) is a chronic psychiatric disorder characterized by recurrent intrusive thoughts and/or repetitive compulsory behaviors. This psychiatric disorder is known to be stress responsive, as symptoms increase during periods of stress but also because stressful events may precede the onset of OCD. However, only a few and inconsistent reports have been published about the stress perception and the stress response in these patients. Herein, we have characterized the correlations of OCD symptoms with basal serum cortisol levels and scores in a stress perceived questionnaire (PSS-10). The present data reveals that cortisol levels and the stress scores in the PSS-10 were significantly higher in OCD patients that in controls. Moreover, stress levels self-reported by patients using the PSS-10 correlated positively with OCD severity in the Y-BOCS. Interestingly, PSS-10 scores correlated with the obsessive component, but not with the compulsive component, of Y-BOCS. These results confirm that stress is relevant in the context of OCD, particularly for the obsessive symptomatology.Keywords
This publication has 32 references indexed in Scilit:
- Stress-induced changes in human decision-making are reversibleTranslational Psychiatry, 2012
- Stress Transiently Affects Pavlovian-to-Instrumental TransferFrontiers in Neuroscience, 2012
- Stressful life events at onset of obsessive-compulsive disorder are associated with a distinct clinical patternDepression and Anxiety, 2011
- Onset and Exacerbation of Obsessive-Compulsive Disorder in Pregnancy and the Postpartum PeriodBritish Journal of Psychology, 2010
- Quality of Life Outcomes in Patients With Obsessive-Compulsive DisorderBritish Journal of Psychology, 2010
- The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey ReplicationMolecular Psychiatry, 2008
- An investigation of traumatic life events and obsessive-compulsive disorderBehaviour Research and Therapy, 2007
- Childhood trauma in obsessive-compulsive disorder, trichotillomania, and controlsDepression and Anxiety, 2002
- Dexamethasone Suppression Test in Patients with Primary Obsessive-Compulsive Disorder and in Healthy ControlsNeuropsychobiology, 1990
- THE ASSESSMENT OF ANXIETY STATES BY RATINGPsychology and Psychotherapy: Theory, Research and Practice, 1959