Modulation of Perineuronal Nets and Parvalbumin with Developmental Song Learning
Open Access
- 14 October 2009
- journal article
- Published by Society for Neuroscience in Journal of Neuroscience
- Vol. 29 (41), 12878-12885
- https://doi.org/10.1523/jneurosci.2974-09.2009
Abstract
Neural circuits and behavior are shaped during developmental phases of maximal plasticity known as sensitive or critical periods. Neural correlates of sensory critical periods have been identified, but their roles remain unclear. Factors that define critical periods in sensorimotor circuits and behavior are not known. Birdsong learning in the zebra finch occurs during a sensitive period similar to that for human speech. We now show that perineuronal nets, which correlate with sensory critical periods, surround parvalbumin-positive neurons in brain areas that are dedicated to singing. The percentage of both total and parvalbumin-positive neurons with perineuronal nets increased with development. In HVC (this acronym is the proper name), a song area important for sensorimotor integration, the percentage of parvalbumin neurons with perineuronal nets correlated with song maturity. Shifting the vocal critical period with tutor song deprivation decreased the percentage of neurons that were parvalbumin positive and the relative staining intensity of both parvalbumin and a component of perineuronal nets. Developmental song learning shares key characteristics with sensory critical periods, suggesting shared underlying mechanisms.Keywords
This publication has 58 references indexed in Scilit:
- Daily and developmental modulation of “premotor” activity in the birdsong systemDevelopmental Neurobiology, 2009
- Top-Down Regulation of Plasticity in the Birdsong System: “Premotor” Activity in the Nucleus HVC Predicts Song Variability Better Than It Predicts Song FeaturesJournal of Neurophysiology, 2008
- HVC Neural Sleep Activity Increases With Development and Parallels Nightly Changes in Song BehaviorJournal of Neurophysiology, 2007
- Developmental Modulation of the Temporal Relationship Between Brain and BehaviorJournal of Neurophysiology, 2007
- Critical period plasticity in local cortical circuitsNature Reviews Neuroscience, 2005
- Calcium‐binding proteins define interneurons in HVC of the zebra finch (Taeniopygia guttata)Journal of Comparative Neurology, 2005
- Sequential Learning From Multiple Tutors and Serial Retuning of Auditory Neurons in a Brain Area Important to Birdsong LearningJournal of Neurophysiology, 2004
- Neural correlates of singing behavior in male zebra finches (Taeniopygia guttata)Journal of Neurobiology, 1998
- Delayed development of song control nuclei in the zebra finch is related to behavioral developmentJournal of Comparative Neurology, 1986
- Parvalbumin in Most γ-Aminobutyric Acid-Containing Neurons of the Rat Cerebral CortexScience, 1986