Anterior uveitis as an atypical presentation of large granular lymphoma in a caracal (Caracal caracal)
- 3 August 2011
- journal article
- case report
- Published by Wiley in Veterinary Ophthalmology
- Vol. 14 (5), 337-340
- https://doi.org/10.1111/j.1463-5224.2011.00905.x
Abstract
An 11-year-old, female, spayed caracal (Caracal caracal) presented with a 3-month history of intermittent anorexia, vomiting, and weight loss. At examination, bilateral anterior uveitis with anisocoria was present. Further examination under general anesthesia revealed the anterior chamber of the right eye contained copious amounts of thick fibrin, hypopyon, and hyphema obscuring the ventral pupil margin and ventral iris. Aqueous paracentesis revealed a cytologic diagnosis of large granular lymphoma. Additional antemortem diagnostics (computed tomography, ultrasound with fine needle aspiration, and cytology) confirmed the diagnosis of multicentric large granular lymphoma with associated intestinal perforation. Necropsy and histopathology confirmed multicentric large granular lymphoma in the right eye, jejunum, mesenteric lymph nodes, and right kidney. Large granular lymphoma in nondomestic felids is likely rare since it has not been previously reported, but should be considered as a differential in any felid species with anterior uveitis or when lymphoma is considered. In the case of this caracal, the use of aqueous paracentesis with cytology was a powerful diagnostic.Keywords
This publication has 8 references indexed in Scilit:
- The Nutrition and Natural History of the Serval (Felis serval) and Caracal (Caracal caracal)Veterinary Clinics of North America: Exotic Animal Practice, 2009
- Neoplasia in Felids at the Knoxville Zoological Gardens, 1979–2003Journal of Zoo and Wildlife Medicine, 2008
- Description of clinical and pathological findings, treatment and outcome of feline large granular lymphocyte lymphoma (1996–2004)*Veterinary and Comparative Oncology, 2008
- TREATMENT OF MALIGNANT LYMPHOMA IN AN AFRICAN LION (PANTHERA LEO)Journal of Zoo and Wildlife Medicine, 2007
- Feline Large Granular Lymphocyte (LGL) Lymphoma with Secondary Leukemia: Primary Intestinal Origin with Predominance of a CD3/CD8αα PhenotypeVeterinary Pathology, 2006
- Multicentric T-cell Lymphoma Associated with Feline Leukemia Virus infection in a Captive Namibian Cheetah (Acinonyx jubatus)Journal of Wildlife Diseases, 2003
- The Histologic Classification of 602 Cases of Feline Lymphoproliferative Disease using the National Cancer Institute Working FormulationJournal of Veterinary Diagnostic Investigation, 2000
- Neoplasia in Zoo AnimalsThe Journal of Zoo Animal Medicine, 1983