Haemodynamics of cardiac arrest and resuscitation
- 1 June 2006
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Current Opinion in Critical Care
- Vol. 12 (3), 198-203
- https://doi.org/10.1097/01.ccx.0000224861.70958.59
Abstract
This review will summarize the available data regarding the haemodynamic changes occurring following cardiac arrest in humans and animal models. Following cardiac arrest due to ventricular fibrillation without cardiopulmonary resuscitation, blood flow exponentially falls but continues for approximately 5 min until the pressure gradient between the aorta and the right heart is completely dissipated. During cardiopulmonary resuscitation forward flow occurs into the aorta during the compression phase. Coronary blood flow is retrograde during the compression phase and antegrade during the decompression phase. Carotid blood flow takes over a minute to reach plateau levels following the initiation of chest compressions, and even brief interruptions of compressions result in a dramatic reduction in carotid blood flow which takes a minute or so to recover to plateau levels when compressions are reinstituted. Coronary perfusion pressure during the release phase of cardiopulmonary resuscitation has been shown to be a powerful predictor of the likelihood of recovery of spontaneous circulation following restoration of electrical activity. Recent studies have provided important insights into the haemodynamics of cardiac arrest and of cardiopulmonary resuscitation which may inform more effective strategies for the management of cardiac arrest in the future.Keywords
This publication has 45 references indexed in Scilit:
- Magnetic Resonance Imaging During Untreated Ventricular Fibrillation Reveals Prompt Right Ventricular Overdistention Without Left Ventricular Volume LossCirculation, 2005
- Static filling pressure in patients during induced ventricular fibrillationAmerican Journal of Physiology-Heart and Circulatory Physiology, 2003
- The critical importance of minimal delay between chest compressions and subsequent defibrillation: a haemodynamic explanationResuscitation, 2003
- Release of endogenous vasopressors during and after cardiopulmonary resuscitation.Heart, 1996
- Plasma catecholamines and resuscitation from prolonged cardiac arrestCritical Care Medicine, 1989
- Plasma catecholamine and serum cortisol responses to experimental cardiac arrest in dogsAmerican Journal of Physiology-Endocrinology and Metabolism, 1987
- SIMULTANEOUS CHEST COMPRESSION AND VENTILATION AT HIGH AIRWAY PRESSURE DURING CARDIOPULMONARY RESUSCITATIONThe Lancet, 1980
- CLOSED-CHEST CARDIAC MASSAGEJAMA, 1960
- Mean Circulatory Filling Pressure Measured Immediately After Cessation of Heart PumpingAmerican Journal of Physiology-Legacy Content, 1954
- RÔLE OF THE “STATIC BLOOD PRESSURE” IN ABNORMAL INCREMENTS OF VENOUS PRESSURE, ESPECIALLY IN HEART FAILURE. II. CLINICAL AND EXPERIMENTAL STUDIESThe American Journal of the Medical Sciences, 1940