COVID-19 with cystic features on computed tomography

Abstract
Rationale: The cystic features of the novel coronavirus disease 2019 (COVID-19) found on computed tomography (CT) have not yet been reported in the published literature. We report the cystic chest CT findings of 2 patients confirmed to have COVID-19-related pneumonia. Patient concerns: A 38-year-old man and a 35-year-old man diagnosed with severe COVID-19 pneumonia were admitted to the intensive care unit. Diagnoses: Chest CT findings showed multiple cysts in ground-glass opacities (bilaterally) with/without pneumothorax. The cysts had a smooth inner wall. Interventions: The patients continued to be given oxygen by mask and received antitussive, phlegm-dispelling treatment. Outcomes: At follow up, there was a reduction in the number of multiple cystic lesions on CT. To date, 1 patient was discharged from hospital, while the other had been transferred to the rehabilitation department. Lessons: COVID-19 may independently result in pulmonary cyst formation and pneumothorax; the application of a ventilator may be another causative factor.
Funding Information
  • Jiangsu Provincial Commission of Health and Family Planning (Z201612)
  • Jiangsu Natural Science Foundation (BK20181179)
  • Jiangsu high level health professional project (LGY2017010)
  • Jiangsu Youth Medical Talent Project (QNRC2016236)
  • Gusu medical professional project (045)