A Facile Synthesis of Substituted Benzyl Selenocyanates†
Open Access
- 31 July 2004
- Vol. 9 (8), 622-626
- https://doi.org/10.3390/90800622
Abstract
Benzyl selenocyanates can be made from the corresponding benzylic bromides or chlorides in 30-60 minutes using acetonitrile as a solvent. The products may be obtained pure in satisfactory yields without recourse to chromatography.Keywords
This publication has 7 references indexed in Scilit:
- Selenium Metabolism and Mechanisms of Cancer PreventionAdvances in experimental medicine and biology, 2001
- Chemoprevention of Colon Cancer by Organoselenium Compounds and Impact of High- or Low-Fat DietsJNCI Journal of the National Cancer Institute, 1997
- Evaluation of organoselenium compounds for potential chemopreventive properties in colon carcinogenesis.1994
- Inhibition of thymidine kinase in cultured mammary tumor cells by the chemopreventive organoselenium compound, 1,4-phenylenebis(methylene)selenocyanateCarcinogenesis: Integrative Cancer Research, 1994
- Inhibition of 7,12-dimethylbenz(a)anthracene-induced tumors and DNA adduct formation in the mammary glands of female Sprague-Dawley rats by the synthetic organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate.1992
- Chemoprevention of experimental mammary carcinogenesis by the synthetic organoselenium compound, benzylselenocyanate, in ratsCarcinogenesis: Integrative Cancer Research, 1989
- Selenocyanation using a combined reagent of triphenylphosphine and selenocyanogen. A new and simple synthesis of alkyl selenocyanates and symmetrical alkyl diselenides from alcoholsTetrahedron Letters, 1979