Evaluating the Impact of a Single-Day Multidisciplinary Clinic on the Management of Pancreatic Cancer
- 7 May 2008
- journal article
- research article
- Published by Springer Science and Business Media LLC in Annals of Surgical Oncology
- Vol. 15 (8), 2081-2088
- https://doi.org/10.1245/s10434-008-9929-7
Abstract
Purpose To evaluate the impact of a multidisciplinary clinic on the clinical care recommendations of patients with pancreatic cancer compared with the recommendations the patients received prior to review by the multidisciplinary tumor board. Methods The records of 203 consecutive patients referred to the Johns Hopkins pancreatic multidisciplinary clinic were prospectively collected from November 2006 to October 2007. Cross-sectional imaging, pathology, and medical history were evaluated by a panel of medical/radiation oncologists, surgical oncologists, pathologists, diagnostic radiologists, and geneticists. Alterations in treatment recommendations between the outside institution and the multidisciplinary clinic were recorded and compared. Results On presentation, the outside computed tomography (CT) report described locally advanced/unresectable disease (34.9%), metastatic disease (17.7%), and locally advanced disease with metastasis (1.1%). On review of submitted imaging and imaging performed at Hopkins, 38 out of 203 (18.7%) patients had a change in the status of their clinical stage. Review of the histological slides by dedicated pancreatic pathologists resulted in changes in the interpretation for 7 of 203 patients (3.4%). Overall, 48 out of 203 (23.6%) patients had a change in their recommended management based on clinical review of their case by the multidisciplinary tumor board. Enrollment into the National Familial Pancreas Tumor Registry increased from 52 out of 106 (49.2%) patients in 2005 to 158 out of 203 (77.8%) with initiation of the multidisciplinary clinic. Conclusion The single-day pancreatic multidisciplinary clinic provided a comprehensive and coordinated evaluation of patients that led to changes in therapeutic recommendations in close to one-quarter of patients.Keywords
This publication has 44 references indexed in Scilit:
- Portal Vein Resection for Advanced Pancreatic Head CancerJournal of the American College of Surgeons, 2007
- Multidisciplinary cancer conferences: A systematic review and development of practice standardsEuropean Journal Of Cancer, 2007
- Changes in surgical management resulting from case review at a breast cancer multidisciplinary tumor boardCancer, 2006
- Borderline Resectable Pancreatic Cancer: Definitions, Management, and Role of Preoperative TherapyAnnals of Surgical Oncology, 2006
- Factors Associated with Enrollment in Cancer Genetics ResearchCancer Epidemiology, Biomarkers & Prevention, 2006
- Systematic Review of Barriers to the Recruitment of Older Patients With Cancer Onto Clinical TrialsJournal of Clinical Oncology, 2005
- Pancreaticoduodenectomy with vascular resection: margin status and survival durationJournal of Gastrointestinal Surgery, 2004
- Prospective Risk of Pancreatic Cancer in Familial Pancreatic Cancer KindredsCancer Research, 2004
- Predicting resectability of periampullary cancer with three-dimensional computed tomographyJournal of Gastrointestinal Surgery, 2004
- Prediction of resectability of pancreatic malignancy by computed tomographyBritish Journal of Surgery, 1998