Halogen bonding in solution
Top Cited Papers
- 14 February 2012
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Chemical Society Reviews
- Vol. 41 (9), 3547-3557
- https://doi.org/10.1039/c2cs15292d
Abstract
Halogen bonding is the electron density donation based weak interaction of halogens with Lewis bases. Its applicability for molecular recognition processes long remained unappreciated and has so far mostly been studied in silico and in solid state. As most physiological processes and chemical reactions take place in solution, investigations in solutions are of highest relevance for its use in the pharmaceutical and material scientific toolboxes. Following a short discussion of the phenomenon of halogen bonding, this tutorial review presents an overview of the methods hitherto applied for gaining an improved understanding of its behaviour in solutions and summarizes the gained knowledge in order to indicate the scope of the techniques and to facilitate exciting future developments.This publication has 80 references indexed in Scilit:
- Halogen‐Bond‐Induced Activation of a Carbon–Heteroatom BondAngewandte Chemie-International Edition, 2011
- Evaluating the Potential for Halogen Bonding in the Oxyanion Hole of Ketosteroid Isomerase Using Unnatural Amino Acid MutagenesisACS Chemical Biology, 2009
- An overview of halogen bondingJournal of Molecular Modeling, 2006
- Halogen bonding: the σ-holeJournal of Molecular Modeling, 2006
- Drug Chirality in AnesthesiaAnesthesiology, 2002
- Perfluorocarbon–hydrocarbon self-assembly: Part 16. 19F NMR study of the halogen bonding between halo-perfluorocarbons and heteroatom containing hydrocarbonsJournal of Fluorine Chemistry, 2002
- HypothesisAnesthesia & Analgesia, 1997
- Fluorocarbon anaesthetics break hydrogen bondsNature, 1974
- The Raman spectra of some iodine, bromine, and iodine monochloride charge-transfer coomplexes in solutionJournal of the American Chemical Society, 1967
- High-resolution Raman spectroscopy in the red and near infrared—II: Vibrational frequencies and molecular interactions of halogens and diatomic interhalogensSpectrochimica Acta, 1961