Small Split Pediatric Kidneys to Expand the Donor Pool: An Analysis of Scientific Registry of Transplant Recipients (SRTR) Data
- 1 December 2019
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Transplantation
- Vol. 103 (12), 2549-2557
- https://doi.org/10.1097/tp.0000000000002706
Abstract
Increased use of pediatric deceased donor kidneys could enlarge the deceased donor kidney pool. Kidney transplant outcomes from small pediatric donors were compared with those from ideal kidney (IK) and expanded criteria kidney (ECK) donors to understand the optimal use of pediatric donor kidneys. Kaplan-Meier analyses compared long term patient and death censored graft survival of en-bloc kidney (EBK) and split kidney (SpK) transplants from small pediatric donors (age ≤8 years and 10 kg were better than with ECK. 3,901 transplants were performed from 3,660 pediatric donors (53% yield). Pediatric kidneys can augment the kidney donor pool and should not be considered ECK. Had 90% of kidneys from donors (age ≤ 8 years and weight < 30 kg) with at least one organ transplanted been used (as SpK when > 10 kg) an additional 159 kidney transplants per year could have been performed. Expanding the use of pediatric kidneys should be further explored by the transplant community.This publication has 36 references indexed in Scilit:
- Pediatric En Bloc Kidney Transplantation to Adult Recipients: More Than Suboptimal?Transplantation, 2010
- Superiority of Pediatric En Bloc Renal Allografts Over Living Donor Kidneys: A Long-term Functional StudyTransplantation, 2006
- Recovery and Utilization of Deceased Donor Kidneys from Small Pediatric DonorsAmerican Journal of Transplantation, 2006
- En-Bloc Kidney Transplantation in the United States: An Analysis of United Network of Organ Sharing (UNOS) Data from 1987 to 2003American Journal of Transplantation, 2005
- Outcome of renal transplants from pediatric donors <5 yr of ageClinical Transplantation, 2005
- Increasing the donor pool using en bloc pediatric kidneys for transplantTransplantation, 2003
- Comparison of Mortality in All Patients on Dialysis, Patients on Dialysis Awaiting Transplantation, and Recipients of a First Cadaveric TransplantThe New England Journal of Medicine, 1999
- OUTCOME OF EN BLOC AND SINGLE KIDNEY TRANSPLANTATION FROM VERY YOUNG CADAVERIC DONORS1,2,3,4,5,6Transplantation, 1997
- Long-term Results with Single Pediatric Donor Kidney Transplants in Adult RecipientsJournal of Urology, 1996
- THE HYPERFILTRATION HYPOTHESIS IN HUMAN RENAL TRANSPLANTATIONTransplantation, 1994