Combined T and B Cell Acute Lymphoblastic Leukaemia
- 12 October 1974
- Vol. 4 (5936), 79-82
- https://doi.org/10.1136/bmj.4.5936.79
Abstract
A case of acute lymphoblastic leukaemia in a 17-year-old male is described. The patient had many distinctive features including a very high blast cell count, prominent lymphadenopathy and hepatosplenomegaly, thymic mass, and a fulminant clinical course. Immunological studies on the blast cells using a variety of techniques showed the presence of two distinct subpopulations, one having the surface characteristics of thymus-dependent (T) lymphoid cells and the other those of bursa-equivalent (B) lymphoid cells. The case therefore represents the first example of a combined T and B cell acute leukaemia.This publication has 22 references indexed in Scilit:
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