Failure of Dual Antimicrobial Therapy in Treatment of Gonorrhea
Top Cited Papers
- 23 June 2016
- journal article
- letter
- Published by Massachusetts Medical Society in The New England Journal of Medicine
- Vol. 374 (25), 2504-2506
- https://doi.org/10.1056/nejmc1512757
Abstract
Resistance to all antimicrobial agents has developed in some Neisseria gonorrhoeae strains. Dual antimicrobial therapy (ceftriaxone plus azithromycin) is a recommended first-line empirical treatment in many countries.1-3 We describe treatment failure with dual therapy in a patient with gonorrhea.Keywords
This publication has 5 references indexed in Scilit:
- Current and future antimicrobial treatment of gonorrhoea – the rapidly evolving Neisseria gonorrhoeae continues to challengeBMC Infectious Diseases, 2015
- Azithromycin Resistance and Its Mechanism in Neisseria gonorrhoeae Strains in Hyogo, JapanAntimicrobial Agents and Chemotherapy, 2015
- Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and FutureClinical Microbiology Reviews, 2014
- Antimicrobial Resistance and Molecular Typing of Neisseria gonorrhoeae Isolates in Kyoto and Osaka, Japan, 2010 to 2012: Intensified Surveillance after Identification of the First Strain (H041) with High-Level Ceftriaxone ResistanceAntimicrobial Agents and Chemotherapy, 2013
- The Emerging Threat of Untreatable Gonococcal InfectionThe New England Journal of Medicine, 2012